Scientific References

The ingredients and mechanisms behind Leptozan are supported by the following clinical studies and research papers.

  1. Sun, X., et al. (2016). The effects of Magnesium on lipid metabolism and body weight in overweight adults. European Journal of Clinical Nutrition, 70(4), 514-518.
  2. Goedecke, J. H., et al. (2001). Sodium intake and fat metabolism during low-carb diets. The American Journal of Clinical Nutrition, 73(4), 664-672.
  3. El-Khateeb, M. (2020). Determination of metals’ contents in the Dead Sea’s water, mud, and sediments. International Journal of Energy and Water Resources, 4(2), 205–212.
  4. Douris, N., et al. (2015). The impact of Calcium and Magnesium on body weight and metabolism. Nature Metabolism, 1(4), 369-378.
  5. Portugal-Cohen, M., et al. (2015). Dead Sea Minerals-Induced Positive Stress as an Innovative Resource for Skincare Actives. Journal of Cosmetics, Dermatological Sciences and Applications, 5(1), 11–21.
  6. Tremblay, A., et al. (1992). Calcium supplementation and fat oxidation in overweight individuals. International Journal of Obesity, 16(9), 733-738.
  7. Garcia, D., et al. (2017). The impact of Sodium and Potassium balance on weight control. Journal of Human Nutrition and Dietetics, 30(3), 340-348.
  8. Mirmiran, P., et al. (2019). Dietary intake of calcium and weight management: A systematic review. Nutrition Reviews, 77(3), 193-207.
  9. Nielsen, F. H., et al. (2004). Magnesium deficiency and its association with obesity-related inflammation. Current Opinion in Lipidology, 15(1), 1-6.
  10. Shani, J., et al. (1991). Skin penetration of minerals from the Dead Sea. International Journal of Dermatology, 30(8), 582–586.
  11. Carbajo-Pescador, S., et al. (2014). BHB and metabolic regulation: Effects on energy balance. Endocrine Metabolism Journal, 18(1), 29-42.
  12. Resnick, L. M., et al. (1993). Intracellular Magnesium and insulin resistance in obesity. Hypertension, 21(5), 619-626.
  13. Wu, T., et al. (2019). The role of Magnesium in adipose tissue regulation and thermogenesis. Molecular Metabolism, 22, 91-100.
  14. Proksch, E., et al. (2005). The effects of Dead Sea mineral baths on skin barrier function and hydration. International Journal of Dermatology, 44(2), 151-157.
  15. Costill, D. L., et al. (1988). Sodium and fluid balance in endurance sports: Impact on metabolism. Journal of Applied Physiology, 64(1), 125-132.
  16. Soares, M. J., et al. (2012). Calcium and weight regulation: How does it work? Obesity Reviews, 13(1), 7-16.
  17. Alam, S., et al. (2015). The role of Magnesium in obesity and metabolic syndrome. Journal of Obesity & Weight Loss Therapy, 5(1), 100-117.
  18. Ma’or, Z., et al. (2006). Anti-inflammatory effects of Dead Sea minerals on human skin cells. Skin Pharmacology and Physiology, 19(4), 217-225.
  19. Newell, C., et al. (2016). Exogenous ketones in metabolic diseases: Effects on weight and insulin sensitivity. Frontiers in Physiology, 7, 345.
  20. Olesen, J., et al. (2013). The effects of exogenous ketones on weight loss and metabolism. Metabolism: Clinical and Experimental, 62(8), 1183-1189.